#PainStopsHere

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Potential Side Effects of Opioid Medications

Potential Side Effects of Opioid Medications

To the user

  • Misuse
  • Substance use disorder (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition)
  • Overdose death
  • Respiratory depression
  • Somnolence and sedation
  • Withdrawal if abruptly stopped
  • Constipation
  • Androgen deficiency
  • Depression and anxiety
  • Opioid-induced hyperalgesia
  • Urinary retention
  • Nausea and vomiting
  • Hypotension
  • Liver toxicity
  • Pruritus

To the pregnant user’s fetus or newborn

  • Preterm delivery
  • Congenital defects: heart, neural tube, etc
  • Neonatal abstinence syndrome
  • Multiple other possible effects